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CD11b 抗体 (N-Term)

This anti-CD11b antibody is a 兔 多克隆 antibody detecting CD11b in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3031366
发货至: 中国

Quick Overview for CD11b 抗体 (N-Term) (ABIN3031366)

抗原

See all CD11b (ITGAM) 抗体
CD11b (ITGAM) (Integrin alpha M (ITGAM))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CD11b antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    纯化方法

    Antigen affinity

    免疫原

    An amino acid sequence from the N-terminus of human CD11b (MEQLKKSKTLFSLMQY) was used as the immunogen for this CD11b antibody.

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the CD11b antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the CD11b antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    CD11b (ITGAM) (Integrin alpha M (ITGAM))

    别名

    CD11b

    背景

    ITGAM (Integrin Alpha-M), also called CD11b, MAC-1 or Mo1 alpha subunit (MO1A), is one protein subunit that forms the heterodimeric integrin alpha-M beta-2(alphaMbeta2) molecule. A major surface antigen family on human leukocytes includes complement receptor type 3(CR3A, also called ITGAM, Mac1, or Mo1), lymphocyte function-associated(LFA) antigen type 1 (ITGAL), and p150, 95 (ITGAX). By in situ hybridization, Corbi et al.(1988) demonstrated that the genes encoding the alpha subunits of LFA1(ITGAL), Mac1, and p150, 95(ITGAX), all of which are involved in leukocyte adhesion, constitute a cluster on 16p13.1-p11. Callen et al.(1991) narrowed the assignment to 16p11.2. Inflammation plays an essential role in the initiation and progression of atherosclerosis. Simon et al.(2000) presented evidence that it also has a role in vascular repair after mechanical arterial injury (i.e., percutaneous transluminal coronary angioplasty, or PTCA).

    UniProt

    P11215

    途径

    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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