POLK 抗体 (AA 817-830)
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Quick Overview for POLK 抗体 (AA 817-830) (ABIN303130)
抗原
See all POLK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 817-830
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纯化方法
- Immunoaffinity Chromatography.
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免疫原
- Synthetic peptide corresponding to Amino acids 817-830 of Human POLK (polymerase (DNA directed) kappa).
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anti-Polymerase (DNA Directed) kappa (POLK) (AA 1-472) antibody
POLK 适用: 人 WB, ELISA, IF, IHC (p), RNAi 宿主: 小鼠 Monoclonal 6F2 unconjugated
anti-Polymerase (DNA Directed) kappa (POLK) (AA 1-472) antibodyPOLK 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Polymerase (DNA Directed) kappa (POLK) (AA 1-472) antibodyPOLK 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 4F12 unconjugated
anti-Polymerase (DNA Directed) kappa (POLK) (AA 1-473) antibodyPOLK 适用: 人 WB, ELISA, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 6F2 unconjugated
anti-Polymerase (DNA Directed) kappa (POLK) antibodyPOLK 适用: 人, 小鼠, 大鼠 WB, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed) kappa (POLK) (AA 1-472) antibodyPOLK 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed) kappa (POLK) (AA 1-472) antibodyPOLK 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Polymerase (DNA Directed) kappa (POLK) (AA 227-337) antibodyPOLK 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed) kappa (POLK) (AA 1-100) antibodyPOLK 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed) kappa (POLK) (AA 35-84) antibodyPOLK 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry on Paraffin Sections (5 μg/mL). Immunofluorescence. Western Blot (1/500-1/3000). ELISA (1/2000-1/10000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.8 mg/mL
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缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at-20 °C. Dilute only prior to immediate use.
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- POLK (Polymerase (DNA Directed) kappa (POLK))
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别名
- DNA Polymerase kappa
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背景
- POLK (also known as DNA polymerase kappa, DINB protein and DINP) is involved in DNA repair. POLK plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. POLK lacks 3'-5' proofreading exonuclease activity. POLK is a nuclear protein that binds to REV1L and PCNA. POLK is detected throughout the nucleus and at replication foci. Multiple alternative splice variants have been detected for this protein. POLK is found at low levels in testis, spleen, prostate and ovary and at very low levels in kidney, colon, brain, heart, liver, lung, placenta, pancreas and peripheral blood leukocytes.Synonyms: DINB protein, DINB1, DINP, POLK
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基因ID
- 51426
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NCBI登录号
- NP_057302
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UniProt
- Q9UBT6
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途径
- DNA Damage Repair
抗原
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