GJB2 抗体 (N-Term)
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Quick Overview for GJB2 抗体 (N-Term) (ABIN3031025)
抗原
See all GJB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Antigen affinity
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免疫原
- An amino acid sequence from the N-terminus of human GJB2 (MDWGTLQTILGGVNKH) was used as the immunogen for this GJB2 antibody.
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亚型
- IgG
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anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (AA 99-131) antibody
GJB2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (C-Term) antibodyVerified GJB2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (AA 1-226) antibodyGJB2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C6 unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (Cytoplasmic Domain) antibodyGJB2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal CX-12H10 unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) antibodyGJB2 适用: 人, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (Internal Region) antibodyGJB2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (Internal Region) antibodyGJB2 适用: 人, 小鼠, 大鼠 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (AA 85-134) antibodyGJB2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (N-Term) antibodyGJB2 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (Middle Region) antibodyGJB2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the GJB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the GJB2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))
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别名
- GJB2
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背景
- Connexin26(CX26), also known as GAP junction protein, beta2, GJB2. Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. The 3-prime untranslated region of the CX26 transcript contains a putative mRNA instability sequence. The deduced 226-amino acid protein has a calculated molecular mass of about 26 kD. CX26 shares 92.5 % identity with rat Cx26. connexin 26(GJB2) is assigned to human chromosome 13q11-q12 .Connexin 26 regulates epidermal barrier and wound remodeling and promotes psoriasiform response. Connexin 26 gene(GJB2) mutation modulates the severity of hearing loss associated with the 1555A-G mitochondrial mutation.
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UniProt
- P29033
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途径
- Sensory Perception of Sound, Cell-Cell Junction Organization
抗原
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