Dopamine Receptor d1 抗体 (AA 221-242)
Quick Overview for Dopamine Receptor d1 抗体 (AA 221-242) (ABIN3030766)
抗原
See all Dopamine Receptor d1 (DRD1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 221-242
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纯化方法
- Antigen affinity
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免疫原
- Amino acids 221-242 (AQKQIRRIAALERAAVHAKNCQ-human) were used as the immunogen for this DRD1 antibody.
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亚型
- IgG
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anti-Dopamine Receptor D1 (DRD1) (AA 338-446) antibody
DRD1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D1 (DRD1) (AA 101-200) antibodyDRD1 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D1 (DRD1) (AA 11-100) antibodyDRD1 适用: 人, 大鼠 WB, ELISA, ICC, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D1 (DRD1) (AA 338-446) antibodyDRD1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D1 (DRD1) (N-Term) antibodyDRD1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D1 (DRD1) (C-Term) antibodyDRD1 适用: 人 WB, ICC, IF, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D1 (DRD1) (AA 338-446) antibodyDRD1 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D1 (DRD1) (C-Term) antibodyDRD1 适用: 人, 猴, 兔 IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D1 (DRD1) (C-Term) antibodyDRD1 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D1 (DRD1) (Extracellular Domain) antibodyDRD1 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the Dopamine Receptor D1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- The DRD1 antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freeze/thaws.
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- Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))
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别名
- DRD1 Dopamine Receptor D1
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背景
- Dopamine receptor D1 is the most highly expressed DA receptor subtype among the DA receptor family. Receptors for dopamine have been classified into two functional types, D1 and D2. They belong to the family of receptors acting through G (or guanine nucleotide-binding) proteins. D2Rs inhibit adenylyl cyclase, but D1Rs stimulate adenylyl cyclase and activate cyclic AMP-dependent protein kinases. DRD1/2 are targets of drug therapy in many psychomotor disorders, including Parkinson's disease and schizophrenia, and may also have a role in drug addiction and alcoholism. D1Rs regulate neuron growth and differentiation, influence behaviour and modify DRD2-mediated events. And the presence of a DRD1 gene restriction fragment length polymorphism will be helpful for future disease linkage studies. This protein also regulates the neurochemical architecture of the striatum and is critical for the normal expression of motor activity.
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UniProt
- P21728
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途径
- cAMP Metabolic Process, Inositol Metabolic Process, Protein targeting to Nucleus, Feeding Behaviour, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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