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Caspase 2 抗体 (AA 417-439)

CASP2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030294
发货至: 中国
  • 抗原 See all Caspase 2 (CASP2) 抗体
    Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
    抗原表位
    • 15
    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 417-439
    适用
    • 97
    • 37
    • 24
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 89
    • 6
    • 4
    克隆类型
    • 79
    • 20
    多克隆
    标记
    • 57
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Caspase 2 antibody is un-conjugated
    应用范围
    • 71
    • 34
    • 23
    • 14
    • 14
    • 13
    • 9
    • 7
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    Amino acids 417-439 (REGYAPGTEFHRCKEMSEYCSTL) were used as the immunogen for this Caspase-2 antibody (100% homologous in human, mouse and rat). This sequence is from the small subunit.
    亚型
    IgG
    Top Product
    Discover our top product CASP2 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting points. Titration of the Caspase-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the Caspase-2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
    别名
    Caspase-2 (CASP2 产品)
    别名
    xCaspase-2 antibody, Caspase-2 antibody, ICH-1 antibody, Nedd2 antibody, CASP-2 antibody, ICH1 antibody, NEDD-2 antibody, NEDD2 antibody, PPP1R57 antibody, ICH-1L/1S antibody, ICH1L1S antibody, caspase 2 antibody, caspase 2 L homeolog antibody, caspase-2 antibody, CASP2 antibody, casp2.L antibody, CpipJ_CPIJ008254 antibody, Casp2 antibody
    背景
    Caspase-2/CASP2, which is involved in stress-induced apoptosis, is recruited into a large protein complex, the molecular composition of which remains elusive. Activation of Caspase-2 occurs in a complex that contains the death domain-containing protein PIDD, whose expression is induced by p53, and the adaptor protein RAIDD. Increased PIDD expression resulted in spontaneous activation of Caspase-2 and sensitization to apoptosis by genotoxic stimuli. CASP2 acts both as a positive and negative cell death effector, depending upon cell lineage and stage of development.
    UniProt
    P42575
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway
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