Aurora A 抗体
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北京 101111
Quick Overview for Aurora A 抗体 (ABIN303027)
抗原
See all Aurora A (AURKA) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody reacts to the C Terminus of Aurora kinase A / STK15: peptide sequence (QNKESASKQS).
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纯化方法
- Immunoaffinity Chromatography
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免疫原
- Synthetic peptide
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anti-Aurora Kinase A (AURKA) (AA 1-110) antibody
AURKA 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 5F8 unconjugated
anti-Aurora Kinase A (AURKA) (AA 268-404) antibodyAURKA 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 2D8A4 unconjugated
anti-Aurora Kinase A (AURKA) (C-Term) antibodyAURKA 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aurora Kinase A (AURKA) (AA 364-392), (C-Term) antibodyAURKA 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB6834 unconjugated
anti-Aurora Kinase A (AURKA) antibodyAURKA 适用: 人, 大鼠, 猴 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1F8 unconjugated
anti-Aurora Kinase A (AURKA) (pThr288) antibodyAURKA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aurora Kinase A (AURKA) antibodyAURKA 适用: 人, 大鼠, 猴 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 4G10 unconjugated
anti-Aurora Kinase A (AURKA) (AA 268-404) antibodyAURKA 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 4H5A8 unconjugated
anti-Aurora Kinase A (AURKA) (AA 364-392) antibodyAURKA 适用: 人 WB, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Aurora Kinase A (AURKA) (AA 1-131) antibodyAURKA 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry on paraffin sectons: 10 μg/mL. Western Blot: 0,5 - 2 μg/mL. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris buffered saline containing 0.5 % BSA and 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- Aurora A (AURKA) (Aurora Kinase A (AURKA))
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别名
- Aurora Kinase A
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背景
- ARK1, an Aurora/IPL1-like protein kinase, functions in centrosome separation, duplication, and maturation and in bipolar spindle assembly and stability. The protein has been shown to localize to centrosomes in S phase as soon as centrioles have been duplicated, and to be degraded in early G1. ARK1 phosphorylation is induced by okadaic acid treatment in vivo. Activated ARK1 has been shown to phosphorylate the spindle apparatus-associated protein, TPX2, and it is believed to be targeted to the spindle apparatus by this protein. At least three alternative splice forms have been reported, however, the alternative splice sites are located in the 5'-untranslated region and appear to have no effect on protein translation. ARK1 has been identified as an oncogene that is overexpressed in several types of solid tumors and tumor cell lines, including those from breast and colon. Additionally, overexpression of ARK1 has been implicated in mechanisms leading to mitotic spindle aberrations, aneuploidy, and genomic instability.Synonyms: AIK1, ARK1, AURA, AURKA, AURORA2, Aurora/IPL1-related kinase 1, BTAK, Breast tumor-amplified kinase, STK15, STK6, Serine/threonine kinase 15, Serine/threonine-protein kinase 6
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基因ID
- 6790
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NCBI登录号
- NP_003591
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UniProt
- O14965
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途径
- Cell Division Cycle, Asymmetric Protein Localization
抗原
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