CTBP1 抗体 (AA 425-440)
-
- 抗原 See all CTBP1 抗体
- CTBP1 (C-terminal Binding Protein 1 (CTBP1))
-
抗原表位
- AA 425-440
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This CTBP1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Antigen affinity
- 免疫原
- Amino acids 425-440 (QTVKPEADRDHASDQL-human) were used as the immunogen for this CtBP1 antibody.
- 亚型
- IgG
- Top Product
- Discover our top product CTBP1 Primary Antibody
-
anti-C-terminal Binding Protein 1 (CTBP1) (AA 1-429) antibody
CTBP1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2G7 unconjugated
anti-C-terminal Binding Protein 1 (CTBP1) (AA 20-250) antibodyCTBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-C-terminal Binding Protein 1 (CTBP1) (C-Term) antibodyCTBP1 适用: 人, 小鼠, 大鼠, 犬, Pig, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-C-terminal Binding Protein 1 (CTBP1) (AA 413-440) antibodyCTBP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-C-terminal Binding Protein 1 (CTBP1) antibodyCTBP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-C-terminal Binding Protein 1 (CTBP1) (Internal Region) antibodyCTBP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-C-terminal Binding Protein 1 (CTBP1) (pSer422) antibodyCTBP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-C-terminal Binding Protein 1 (CTBP1) (C-Term) antibodyCTBP1 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-C-terminal Binding Protein 1 (CTBP1) (AA 409-440), (C-Term) antibodyCTBP1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-C-terminal Binding Protein 1 (CTBP1) (AA 351-440) antibodyCTBP1 适用: 小鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- The stated application concentrations are suggested starting amounts. Titration of the CtBP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- 限制
- 仅限研究用
-
- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the CtBP1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
- 抗原
- CTBP1 (C-terminal Binding Protein 1 (CTBP1))
- 别名
- CtBP1 (CTBP1 产品)
- 别名
- BARS antibody, CtBP1-L antibody, CtBP1-S antibody, CtBP3/BARS antibody, D4S115h antibody, D5H4S115 antibody, D5H4S115E antibody, 50-kDaBFA-inducedADP-ribosylatedsubstrate antibody, BARS-50 antibody, Bars antibody, wu:fi43a11 antibody, CtBP antibody, ctbp1-A antibody, xctbp1 antibody, bars antibody, CTBP1 antibody, C-terminal binding protein 1 antibody, C-terminal binding protein 1 L homeolog antibody, CTBP1 antibody, Ctbp1 antibody, ctbp1 antibody, ctbp1.L antibody
- 背景
- C-terminal-binding protein 1 is encoded by the CTBP1 gene. It binds to the C-terminus of adenovirus E1A proteins. It is a transcriptional repressor(corepressor) and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. CtBP1 and CtBP2 preferentially associate with the E1A via a 5 amino acid motif, PLDLS, to repress E1A induced oncogenesis and cellular transformation. CtBP1 is expressed from embryo to adult, but CtBP2 is mainly expressed during embryogenesis. During skeletal and T cell development, CtBP1 and -2 associate with the PLDLSL domain of delta EF1, a cellular zinc finger-homeodomain protein, and thereby enhances delta EF1-induced transcriptional silencing. In addition, CtBP complexes with CtIP, a 125 kDa protein that recognizes distinctly different protein motifs from CtBP. CtIP binds to the BRCT repeats within the breast cancer gene BRCA1 and enables CtBP to influence BRCA1 activity. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.
- UniProt
- Q13363
- 途径
- Retinoic Acid Receptor Signaling Pathway
-
