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c-FOS 抗体 (AA 170-187)

This anti-c-FOS antibody is a 兔 多克隆 antibody detecting c-FOS in WB. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN3030221
发货至: 中国

Quick Overview for c-FOS 抗体 (AA 170-187) (ABIN3030221)

抗原

See all c-FOS (c-Fos) 抗体
c-FOS (c-Fos) (c-Fos)

适用

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人, 大鼠, 小鼠

宿主

  • 186
  • 22
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  • 1

克隆类型

  • 189
  • 24
  • 1
多克隆

标记

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This c-FOS antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 170-187

    纯化方法

    Antigen affinity

    免疫原

    Amino acids 170-187 (DQLEDEKSALQTEIANLL) were used as the immunogen for this c-Fos antibody (100% homologous in human, mouse and rat).

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the c-Fos antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the c-Fos antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    c-FOS (c-Fos) (c-Fos)

    别名

    C-Fos

    背景

    The human oncogene c-Fos is the cellular homolog of the transforming gene of Finkel-Biskis-Jinkins(FBJ) murine osteosarcoma virus which was mapped to a single human chromosome. The protein is encoded by the FOS gene. It was the first transcription factor identified that has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is also a major component of the activator protein-1 (AP-1) transcription factor complex, which includes members of the JUN family. c-Fos is a major nuclear target for signal transduction pathways involved in the regulation of cell growth, differentiation, and transformation. Using transgenic and knockout mice, Grigoriadis et al.(1995) established a unique role for the proto-oncogene and nuclear transcription factor in regulating the differentiation and activity of specific bone cell populations, both during normal development and in bone disease.

    UniProt

    P01100

    途径

    S100 Proteins
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