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BAG2 抗体 (N-Term)

This anti-BAG2 antibody is a 兔 多克隆 antibody detecting BAG2 in WB. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN3030137
发货至: 中国

Quick Overview for BAG2 抗体 (N-Term) (ABIN3030137)

抗原

See all BAG2 抗体
BAG2 (BCL2-Associated Athanogene 2 (BAG2))

适用

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人, 大鼠, 小鼠

宿主

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  • 1

克隆类型

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多克隆

标记

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This BAG2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    纯化方法

    Antigen affinity

    免疫原

    An amino acid sequence from the N-terminus of human BAG family molecular chaperone regulator 2 (MAQAKINAKANEGR) was used as the immunogen for this BAG2 antibody.

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the BAG2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the BAG2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    BAG2 (BCL2-Associated Athanogene 2 (BAG2))

    别名

    BAG2

    背景

    BAG family molecular chaperone regulator 2 is a protein that in humans is encoded by the BAG2 gene. The predicted protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All three proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. The functional antagonisms displayed between BAG family proteins and Hip suggest that a proper balance of these two types of protein is required for achieving optimal cycles of substrate binding and release required for inducting conformational changes in proteins, with Hip promoting peptide substrate binding by Hsc70/Hsp70 and BAG family proteins promoting dissociation.

    UniProt

    O95816
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