ATG7 抗体 (AA 652-669)
Our Local Distributor
北京 101111
Quick Overview for ATG7 抗体 (AA 652-669) (ABIN3030040)
抗原
See all ATG7 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 652-669
-
纯化方法
- Antigen affinity
-
免疫原
- Amino acids 652-669 (KVLDQYEREGFNFLAKVF-human) were used as the immunogen for this ATG7 antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Titration of the ATG7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
-
限制
- 仅限研究用
-
-
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- -20 °C
-
储存方法
- After reconstitution, the ATG7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
-
- ATG7 (ATG7 Autophagy Related 7 (ATG7))
-
别名
- ATG7
-
背景
- Autophagy-related protein 7 is a protein that in humans is encoded by the ATG7 gene. This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein also shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes. ATG7 is essential for the Apg12 conjugation system that mediates membrane fusion in autophagy. It is found that when nutrients are limited, the protein can regulate p53-dependent cell cycle and cell death pathways.
-
UniProt
- O95352
-
途径
- Response to Water Deprivation, Autophagy
抗原
-