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Aryl Hydrocarbon Receptor 抗体 (AA 832-848)

The 兔 多克隆 anti-Aryl Hydrocarbon Receptor antibody (ABIN3030027) specifically detects Aryl Hydrocarbon Receptor in WB. The antibody is reactive with 人 samples.
产品编号 ABIN3030027
发货至: 中国
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Quick Overview for Aryl Hydrocarbon Receptor 抗体 (AA 832-848) (ABIN3030027)

抗原

See all Aryl Hydrocarbon Receptor (AHR) 抗体
Aryl Hydrocarbon Receptor (AHR)

适用

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宿主

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克隆类型

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多克隆

标记

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This Aryl Hydrocarbon Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 832-848

    纯化方法

    Antigen affinity

    免疫原

    Amino acids 832-848 (HPSEARPFPDLTSSGFL-human) were used as the immunogen for this Aryl hydrocarbon Receptor antibody.

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the Aryl hydrocarbon Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the Aryl hydrocarbon Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    Aryl Hydrocarbon Receptor (AHR)

    背景

    Aryl hydrocarbon receptor, also called AHR and bHLHe76, is a member of the family of basic helix-loop-helix transcription factors. It is a cytosolic transcription factor that is normally inactive, bound to several co-chaperones. The gene is mapped on 7p21.1. Estrogenic actions of AHR agonists were detected in wildtype ovariectomized mouse uteri, but were absent in Ahr-/- or Er-alpha -/- ovariectomized mice. CD4-positive cells from mice lacking the recepter developed Th17 responses but failed to produce IL-22 and did not show enhanced Th17 development. Activation of Aryl hydrocarbon receptor during induction of EAE accelerated disease onset and increased pathology in wildtype mice, but not in -/- mice. The TDO-AHR pathway is active in human brain tumors and is associated with malignant progression and poor survival. Activity within ROR-gamma-t-positive ILC could be induced by dietary ligands such as those contained in vegetables of the family Brassicaceae.

    UniProt

    P35869

    途径

    Regulation of Cell Size
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