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Angiopoietin 2 抗体 (AA 454-468)

ANGPT2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3029949
发货至: 中国
  • 抗原 See all Angiopoietin 2 (ANGPT2) 抗体
    Angiopoietin 2 (ANGPT2)
    抗原表位
    • 15
    • 10
    • 7
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
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    AA 454-468
    适用
    • 75
    • 37
    • 26
    • 4
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 77
    • 10
    • 4
    • 1
    • 1
    • 1
    克隆类型
    • 68
    • 26
    多克隆
    标记
    • 48
    • 10
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Angiopoietin 2 antibody is un-conjugated
    应用范围
    • 64
    • 32
    • 32
    • 13
    • 13
    • 12
    • 10
    • 10
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    Amino acids 454-468 (NLNGMYYPQRQNTNK-human) were used as the immunogen for this Angiopoietin 2 antibody.
    亚型
    IgG
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  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the Angiopoietin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the Angiopoietin 2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    Angiopoietin 2 (ANGPT2)
    别名
    Angiopoietin 2 (ANGPT2 产品)
    别名
    AGPT2 antibody, ANG2 antibody, Agpt2 antibody, Ang-2 antibody, Ang2 antibody, ang2 antibody, angpt2 antibody, ANGIOPOIETIN-2 antibody, ANG-2 antibody, ANGPT2 antibody, Angrp antibody, Rnase5b antibody, ANG3 antibody, C11orf2 antibody, C11orf3 antibody, FFR antibody, angiopoietin 2 antibody, angiopoietin 2b antibody, angiogenin, ribonuclease A family, member 2 antibody, VPS51, GARP complex subunit antibody, ANGPT2 antibody, Angpt2 antibody, angpt2b antibody, Ang2 antibody, VPS51 antibody
    背景
    Angiopoietin 2 and -1 are involved in the development of the endothelium by regulating tyrosine phosphorylation of the membrane receptor Tie 2. Angiopoietin 2 is only 60 % homologous with -1. It is a naturally occurring antagonist of ANGPT1 that competes for binding to the TIE2 receptor and blocks ANGPT1-induced TIE2 autophosphorylation. ANGPT1 binding to Tie 2 causes phosphorylation of the receptor. Angiopoietin 2 competes for this binding, and thus blocks receptor phosphorylation. Angiopoietin 2 expression occurs at sites of vascular remodelling: dorsal aorta and major aortic branches, ovary, placenta and uterus.
    UniProt
    O15123
    途径
    RTK signaling
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