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APP 抗体 (C-Term)

This anti-APP antibody is a 兔 多克隆 antibody detecting APP in WB, IHC (p) 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3029934
发货至: 中国

Quick Overview for APP 抗体 (C-Term) (ABIN3029934)

抗原

See all APP 抗体
APP (Amyloid beta (A4) Precursor Protein (APP))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This APP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
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    C-Term

    纯化方法

    Antigen affinity

    免疫原

    An amino acid sequence from the C-terminus of human APP (DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA) was used as the immunogen for this Amyloid beta antibody.

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the Amyloid beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the Amyloid beta antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    APP (Amyloid beta (A4) Precursor Protein (APP))

    别名

    Amyloid beta (APP)

    背景

    Amyloid beta, also called Abeta and APP, denotes peptides that are crucially involved in Alzheimers disease as the main component of the amyloid plaques found in the brains of Alzheimer patients. Several potential activities have been discovered for Amyloid beta, including activation of kinase enzymes, functioning as a transcription factor, and anti-microbial activity (potentially associated with it pro-inflammatory activity). Moreover, monomeric Amyloid beta is indicated to protect neurons by quenching metal-inducible oxygen radical generation and thereby inhibiting neurotoxicity.

    基因ID

    351

    UniProt

    P05067

    途径

    Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour
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