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EPH Receptor B3 抗体 (C-Term)

This anti-EPH Receptor B3 antibody is a 兔 多克隆 antibody detecting EPH Receptor B3 in WB 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3029711
发货至: 中国
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Quick Overview for EPH Receptor B3 抗体 (C-Term) (ABIN3029711)

抗原

See all EPH Receptor B3 (EPHB3) 抗体
EPH Receptor B3 (EPHB3)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This EPH Receptor B3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    纯化方法

    Antigen affinity

    免疫原

    An amino acid sequence from the C-terminus of human Eph receptor B3 (SIQDMRLQMNQTLPVQV) was used as the immunogen for this EphB3 antibody (100% homologous in human, mouse and rat).

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the EphB3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the EphB3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    EPH Receptor B3 (EPHB3)

    别名

    EphB3 Ephrin Receptor B3

    背景

    Ephrin Receptor B3, is also known as human embryo kinase2 (HEK2) or Eph-like tyrosine kinase 2 (ETK2) is a member of the EPH/ELK family of tyrosine kinases. The gene encodes a 998-amino acid polypeptide having a single putative transmembrane domain, a secretory signal sequence, and two fibronectin repeats. The gene is mapped to human chromosome 3q21-qter. EphB3 interacts with two ligands of EPH-related kinases (LERKs), LERK2/EFNB1 and LERK5/EFNB2. Coincubation of EphB3- and LERK2-expressing cells induces cell-cell adhesion and aggregation. Additionally, coexpression of the two proteins results in reduced kinase activity of EphB3.

    UniProt

    P54753

    途径

    RTK signaling
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