电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

TLR5 抗体 (C-Term)

The 兔 多克隆 anti-TLR5 antibody is suitable to detect TLR5 in samples from 人 和 小鼠. It has been validated for WB, IHC (p) 和 IF.
产品编号 ABIN302879
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TLR5 抗体 (C-Term) (ABIN302879)

抗原

See all TLR5 抗体
TLR5 (Toll-Like Receptor 5 (TLR5))

适用

  • 103
  • 60
  • 30
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 94
  • 17
  • 3

克隆类型

  • 87
  • 27
多克隆

标记

  • 57
  • 11
  • 11
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TLR5 antibody is un-conjugated

应用范围

  • 89
  • 44
  • 36
  • 13
  • 13
  • 10
  • 7
  • 5
  • 4
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 抗原表位

    • 13
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    This antibody reacts with a peptide corresponding to 15 amino acids near the carboxy terminus of TLR5.

    交叉反应 (详细)

    Species reactivity (expected):Human.
    Species reactivity (tested):Mouse.

    纯化方法

    Affinity Chromatography.

    免疫原

    Synthetic peptide corresponding to 15 amino acids near the carboxy terminus of TLR5.
  • 应用备注

    Western Blot: 1-2 μg/mL. Immunohistochemistry: 5 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    TLR5 (Toll-Like Receptor 5 (TLR5))

    别名

    TLR5

    背景

    The Toll like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans. The TRL family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLRs characterized so far activate the MyD88/interleukin 1 receptor-associated kinase (IRAK) signaling pathway. Toll-like receptor 5 (TLR5) expression is upregulated following exposure to bacteria or to the TLR5 agonist, flagellin. Gram-negative bacteria, stimulate monocyte/macrophage cells in a TLR5-specific, CD14-independent manner. The TLR5 receptor thus appears to be the principal means by which the innate immune system recognizes flagellated bacterial pathogens.Synonyms: TIL3, Toll-like receptor 5, Toll/interleukin-1 receptor-like protein 3

    基因ID

    7100

    NCBI登录号

    NP_003259

    UniProt

    O60602

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
You are here: