Cyclin D1 抗体 (AA 219-238)
Quick Overview for Cyclin D1 抗体 (AA 219-238) (ABIN3028596)
抗原
See all Cyclin D1 (CCND1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 219-238
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纯化方法
 - Antigen affinity
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免疫原
 - Amino acids 219-238 (SPNNFLSCYRTTHFLSRVIK) were used as the immunogen for this Cyclin D1 antibody.
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亚型
 - IgG
 
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应用备注
 - The stated application concentrations are suggested starting points. Titration of the Cyclin D1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
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限制
 - 仅限研究用
 
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缓冲液
 - 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
 - -20 °C
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储存方法
 - After reconstitution, the Cyclin D1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
 
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- Cyclin D1 (CCND1)
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别名
 - Cyclin D1
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背景
 - D-type cyclins are regarded as essential links between cell environment and the core cell cycle machinery. Cyclin D1, the product of the human gene CCND1, is also known as BCL1. Cyclin D1 expression is regulated by the retinoblastoma protein. Expression of Cyclin D1, but not of cyclins A and E, was induced by transfection of the RB gene into RB-deficient tumor cells. The CCND1 gene can function as an oncogene.
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UniProt
 - P25322
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途径
 - PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling
 
抗原
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