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PD-1 抗体 (Center)

This anti-PD-1 antibody is a 兔 多克隆 antibody detecting PD-1 in WB 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN302847
发货至: 中国

Quick Overview for PD-1 抗体 (Center) (ABIN302847)

抗原

See all PD-1 (PDCD1) 抗体
PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This PD-1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 16
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    Center

    特异性

    This antibody is specific to CD279 (PDCD1/PD1).

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Immunoaffinity Chromatography

    免疫原

    Synthetic peptide corresponding to a 16 amino acid peptide from near the center of human PDCD1.
  • 应用备注

    Western Blot: 1 μg/mL. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    DO NOT FREEZE!!

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

    别名

    CD279 / PD1

    背景

    This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.Synonyms: PDCD1, Programmed cell death protein 1, Protein PD-1, hPD-1

    基因ID

    5133

    NCBI登录号

    NP_005009

    UniProt

    Q15116

    途径

    Cancer Immune Checkpoints
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