IL-21 抗体 (Center)
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Quick Overview for IL-21 抗体 (Center) (ABIN302822)
抗原
See all IL-21 (IL21) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody is specific to Interleukin-21 (IL21).
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纯化方法
- Immunoaffinity Chromatography.
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免疫原
- Synthetic peptide corresponding to 15 amino acids near the center of IL-21 precursor.
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应用备注
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Western Blot: 0.5-1.0 μg/mL. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- IL-21 (IL21) (Interleukin 21 (IL21))
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别名
- Interleukin-21 / IL21
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背景
- A novel cytokine was recently identified in Human and Mouse and designated IL-21, which has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21 is expressed in activated T cells, and HL-60 and THP-1 cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.Synonyms: IL-21, Za11
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基因ID
- 59067
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NCBI登录号
- NP_001193935
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UniProt
- Q9HBE4
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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