USP18 抗体
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北京 101111
Quick Overview for USP18 抗体 (ABIN302692)
抗原
See all USP18 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody reacts to amino acids 40 to 49 of human USP18.
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纯化方法
- Immunoaffinity Chromatography
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免疫原
- Synthetic peptide
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应用备注
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Immunofluorescence. Western Blot: 1: 500 - 1: 2000. Immunohistochemistry: 5 μg/mL. ELISA: 1: 10000 - 1: 50000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.93 mg/mL
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缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- USP18 (Ubiquitin Specific Peptidase 18 (USP18))
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别名
- USP18
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背景
- UBP43 (also known as ISG43, Ubl thiolesterase 18, ISG15-specific processing protease, 43 kDa ISG15-specific protease, ubiquitin specific protease 18 or USP18) is a member of the deubiquitinating protease family of enzymes, which removes ubiquitin adducts from a broad range of protein substrates. Deletion of the UBP43 gene in mouse leads to a massive increase of ISG15 conjugates in tissues indicating that UBP43 is a major ISG15-specific protease. UBP43 is the first ISG15-specific protease reported. Both ISG15 and UBP43 genes are known to be strongly induced by interferon, genotoxic stress, and viral infection. Thus UBP43 may be necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms.Synonyms: 43 kDa ISG15-specific protease, ISG15-specific-processing protease, ISG43, Ubl carboxyl-terminal hydrolase 18, Ubl thioesterase 18
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基因ID
- 11274
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NCBI登录号
- NP_059110
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UniProt
- Q9UMW8
抗原
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