IFNA 抗体
Quick Overview for IFNA 抗体 (ABIN3026804)
抗原
See all IFNA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- This mAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.
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纯化方法
- Protein G affinity chromatography
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免疫原
- Purified recombinant human IFNA1 was used as the immunogen for the Interferon alpha antibody.
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亚型
- IgG1 kappa
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anti-Interferon alpha (IFNA) (AA 28-227) antibody
IFNA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) antibodyIFNA 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 24-192) antibodyIFNA 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 24-189) antibodyIFNA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 1-187) antibodyIFNA 适用: 豚鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 24-181) antibodyIFNA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) antibodyIFNA 适用: 大鼠 FACS 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 24-181) antibodyIFNA 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Interferon alpha (IFNA) (AA 47-191) antibodyIFNA 适用: 小鸡 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 23-187) antibodyIFNA 适用: 犬 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Interferon alpha antibody should be determined by the researcher.\. ELISA: order BSA/azide-free format for coating
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Interferon alpha antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- IFNA (Interferon alpha (IFNA))
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别名
- Interferon alpha
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背景
- This mAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.
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途径
- JAK/STAT Signaling, TLR signaling, Hepatitis C, Inflammasome
抗原
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