CD1b 抗体
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北京 101111
Quick Overview for CD1b 抗体 (ABIN3026713)
抗原
See all CD1b (CD1B) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- This antibody recognizes CD1b, a 44 kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1b molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. It is also expressed in interdigitating cells.
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纯化方法
- Protein G affinity chromatography
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免疫原
- Human peripheral lymphocytes were used as the immunogen for this CD1b antibody.
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亚型
- IgG1 kappa
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anti-CD1b (CD1B) antibody
CD1B 适用: 人 FACS, IP, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal SN13 unconjugated
anti-CD1b (CD1B) (AA 18-303) antibodyCD1B 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 5G3D4 unconjugated
anti-CD1b (CD1B) (AA 18-303) antibodyCD1B 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 1D6B7 unconjugated
anti-CD1b (CD1B) antibody (APC)CD1B 适用: 人 FACS 宿主: 小鼠 Monoclonal SN13 APC
anti-CD1b (CD1B) (AA 1-333) antibodyCD1B 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-CD1b (CD1B) antibodyCD1B 适用: 人 FACS, ELISA, IF, Coat 宿主: 小鼠 Monoclonal RIV12 unconjugated
anti-CD1b (CD1B) antibody (FITC)CD1B 适用: 人 FACS 宿主: 小鼠 Monoclonal SN13 FITC
anti-CD1b (CD1B) (AA 18-303) antibodyCD1B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CD1b (CD1B) (AA 18-303) antibodyCD1B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD1b (CD1B) antibodyCD1B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD1b antibody to be titered up or down for optimal performance.\. Functional testing: order BSA/azide free format,IF: 0.5-1 μg/mL,FACS: 0.5-1 μg/million cells in 0.1ml
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the CD1b antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- CD1b (CD1B)
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别名
- CD1b
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背景
- This antibody recognizes CD1b, a 44 kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1b molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. It is also expressed in interdigitating cells.
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基因ID
- 910
抗原
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