-
- 抗原 See all Keratin 10 (KRT10) 抗体
- Keratin 10 (KRT10)
-
适用
- 人, 小鼠
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This Keratin 10 antibody is un-conjugated
-
应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 产品特性
- This antibody recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). cytokeratin 10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of cytokeratin 10 strictly parallels the extent of differentiation, it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, cytokeratin 10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), cytokeratin 10 is detected very frequently. Expression of cytokeratin 10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
- 纯化方法
- Protein G affinity chromatography
- 免疫原
- Skin extract from a human psoriasis patient was used as the immunogen for this Cytokeratin 10 antibody.
- 克隆位点
- LH2
- 亚型
- IgG1
- Top Product
- Discover our top product KRT10 Primary Antibody
-
anti-Keratin 10 (KRT10) (AA 153-456) antibody
KRT10 适用: 人 WB, IHC (p), ELISA, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 10 (KRT10) antibodyKRT10 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼 IHC, WB, FACS, ICC, IHC (fro) 宿主: 小鼠 Monoclonal RKSE60 unconjugated
anti-Keratin 10 (KRT10) (AA 345-454) antibodyKRT10 适用: 人, 小鼠, 大鼠, 猴 IHC, WB, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 3C2F5 unconjugated
anti-Keratin 10 (KRT10) antibodyKRT10 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Keratin 10 (KRT10) antibodyKRT10 适用: 人, 小鼠, 大鼠, 犬, Pig IHC, WB, FACS, ICC, IHC (fro) 宿主: 小鼠 Monoclonal RKSE60 unconjugated
anti-Keratin 10 (KRT10) antibodyKRT10 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (cc) 宿主: 兔 Monoclonal 1D8 unconjugated
anti-Keratin 10 (KRT10) antibodyKRT10 适用: 人, 小鼠 IHC, WB, StM 宿主: 小鼠 Monoclonal LH2 unconjugated
anti-Keratin 10 (KRT10) (Internal Region) antibodyKRT10 适用: 人, 小鼠, 大鼠 IHC, WB, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 10 (KRT10) antibodyKRT10 适用: 人 IHC (p), ICC, IP 宿主: 小鼠 Monoclonal VIK-10 unconjugated
anti-Keratin 10 (KRT10) antibodyKRT10 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-610M unconjugated Recombinant Antibody
-
- 应用备注
-
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.
1. Staining of formalin-fixed tissues requires boiling tissue sections in 1 mM EDTA, pH 8-9, for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. FACS: 0.5-1 μg/million cells,IF: 0.5-1 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1),Prediluted format : incubate for 30 min at RT (2) - 限制
- 仅限研究用
-
- 浓度
- 1 mg/mL
- 缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
- 储存液
- Azide free
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store the Cytokeratin 10 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
-
- 抗原
- Keratin 10 (KRT10)
- 别名
- Cytokeratin 10 (KRT10 产品)
- 别名
- BCIE antibody, BIE antibody, CK10 antibody, EHK antibody, K10 antibody, KPP antibody, D130054E02Rik antibody, K1C1 antibody, Krt-1.10 antibody, Krt1-10 antibody, Ka10 antibody, Ker10 antibody, KRT10 antibody, KRT25 antibody, KRT27 antibody, KRT28 antibody, keratin 10 antibody, keratin 10, type I S homeolog antibody, keratin, type I cytoskeletal 25 antibody, KRT10 antibody, Krt10 antibody, krt10.S antibody, LOC101085587 antibody
- 背景
- This antibody recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). cytokeratin 10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of cytokeratin 10 strictly parallels the extent of differentiation, it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, cytokeratin 10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), cytokeratin 10 is detected very frequently. Expression of cytokeratin 10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
- 基因ID
- 3858
-
You are here:
