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BACE1 抗体 (Internal Region)

This 兔 多克隆 antibody specifically detects BACE1 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN302584
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for BACE1 抗体 (Internal Region) (ABIN302584)

抗原

See all BACE1 抗体
BACE1 (Beta-secretase 1 (BACE1))

适用

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宿主

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克隆类型

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多克隆

标记

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This BACE1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    Internal Region

    特异性

    This antibody deztects Beta-site APP-Cleaving Enzyme 1 (BACE1) at internal domain.

    纯化方法

    Immunoaffinity chromatography

    免疫原

    BACE1 antibody was raised against synthetic peptide from internal domain of human BACE1.
  • 应用备注

    Immunohistochemistry on paraffin sections (2.5 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline containing 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2 °C to 8 °C up to one month or (in aliquots) at -20 °C to -70 °C for longer.
  • 抗原

    BACE1 (Beta-secretase 1 (BACE1))

    别名

    BACE1

    背景

    Bace 1 is responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.Synonyms: ASP2, Aspartyl protease 2, BACE, BACE-1, Beta-secretase 1, Beta-site APP cleaving enzyme 1, Beta-site amyloid precursor protein cleaving enzyme 1, KIAA1149, Memapsin-2, Membrane-associated aspartic protease 2

    基因ID

    23621

    NCBI登录号

    NP_036236

    UniProt

    P56817
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