Metabotropic Glutamate Receptor 5 抗体 (Extracellular Domain, N-Term)
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- 抗原 See all Metabotropic Glutamate Receptor 5 (GRM5) 抗体
- Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))
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抗原表位
- Extracellular Domain, N-Term
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适用
- 大鼠, 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Metabotropic Glutamate Receptor 5 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects Metabotropic Glutamate Receptor 5 (GRM5) at N-terminal extracellular domain.
- 纯化方法
- Immunoaffinity chromatography
- 免疫原
- GRM5 antibody was raised against synthetic 17 amino acid peptide from N-terminal extracellular domain of Human GRM5 / MGLUR5.
- Top Product
- Discover our top product GRM5 Primary Antibody
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anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 458-580) antibody
GRM5 适用: 人 WB, IHC, ELISA, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 1A11D10 unconjugated
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 367-380), (Extracellular), (N-Term) antibodyGRM5 适用: 大鼠, 人, 小鼠 WB, IHC, IF, ICC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 419-518) antibodyGRM5 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibodyGRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-33 unconjugated
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibodyGRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-3 unconjugated
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibody (HRP)GRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-33 HRP
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibody (HRP)GRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-3 HRP
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibody (FITC)GRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-33 FITC
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibody (FITC)GRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-3 FITC
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibody (Alkaline Phosphatase (AP))GRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-3 Alkaline Phosphatase (AP)
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- 应用备注
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Immunohistochemistry on paraffin sections (5.6 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline containing 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
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- 抗原
- Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))
- 别名
- mGluR5 / GRM5 (GRM5 产品)
- 别名
- GPRC1E antibody, MGLUR5 antibody, mGlu5 antibody, mGluR5 antibody, mGlur5 antibody, 6430542K11Rik antibody, AI850523 antibody, Glu5R antibody, Gprc1e antibody, mGluR5b antibody, glutamate receptor, metabotropic 5 antibody, glutamate metabotropic receptor 5 antibody, GRM5 antibody, Grm5 antibody
- 背景
- Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: Ionotropic receptors, and metabotropic receptors (mGluRs). Ionotropic glutamate receptors are oligomeric complexes of various subunits (GluR1 7, NMDA1 3, KAI 2) which comprise ligand gated calcium channels. Metabotropic glutamate receptors are G protein coupled receptors that contain 7 membrane spanning domains and a large extracellular N terminal region. When activated, they can activate phopholipases or adenylylcyclase, depending on the neuron. The group I receptors mGluR1 and mGluR5 activate phospholipase C. By screening a human brain cDNA library with a rat mGluR1 alpha cDNA under low stringency conditions, Minakami et al. (1993) and Minakami et al. (1994) isolated human cDNAs encoding mGluR5. Minakami et al. (1993) identified a longer isoform of mGluR5 (mGluR5B).Synonyms: GPRC1E, MGLUR5, Metabotropic glutamate receptor 5
- 基因ID
- 2915
- NCBI登录号
- NP_000833
- UniProt
- P41594
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
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