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- 抗原 See all NUMA1 抗体
- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This NUMA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- PEG precipitation
- 免疫原
- Colon carcinoma 174T cells were used as the immunogen for the NuMA antibody.
- 克隆位点
- A73-B-D12
- 亚型
- IgM kappa
- Top Product
- Discover our top product NUMA1 Primary Antibody
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anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 1-309) antibody
NUMA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (N-Term) antibodyNUMA1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 627-870) antibodyNUMA1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 1-1193) antibodyNUMA1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 200-306) antibodyNUMA1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1C5 unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 1-1193) antibodyNUMA1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) antibodyNUMA1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (N-Term) antibodyNUMA1 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 1700-2115) antibodyNUMA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 1700-2115) antibodyNUMA1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated
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- 应用备注
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Optimal dilution of the NuMA antibody should be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 min.\. Western blot: 1-2 μg/mL,Immunofluorescence: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
- 储存液
- Azide free
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store the NuMA antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- 抗原
- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
- 别名
- NuMA (NUMA1 产品)
- 背景
- Recognizes a phosphorylated protein of 228 kDa, identified as nuclear mitotic apparatus protein (NuMA). Its epitope is resistant to phosphatases. NuMA is intra-nuclear protein and present in nucleus during interphase. At the onset of mitosis, it redistributes from the nucleus to two centrosomal structures that later will become part of the mitotic spindle pole. After anaphase, the protein redistributes from the spindle polar region into reforming nucleus. NuMA is an essential protein during mitosis for the terminal phases of chromosome separation and/or nuclear reassembly. Recently a study shows that NuMA is cleaved to a 180 to 200 kDa during apoptosis. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 has been detected in patients with acute promyelocytic leukemia.
- 途径
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, M Phase
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