CD28 抗体
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北京 101111
Quick Overview for CD28 抗体 (ABIN3025653)
抗原
See all CD28 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- CD28 Antibody (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- Stimulated human leukocytes were used as the immunogen for the CD28 antibody.
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亚型
- IgG2a, kappa
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应用备注
- Optimal dilution of the CD28 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the CD28 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- CD28
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别名
- CD28
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背景
- Recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
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UniProt
- P10747
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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