HLA DQ 抗体
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北京 101111
Quick Overview for HLA DQ 抗体 (ABIN3025633)
抗原
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- HLA-DQ Antibody (MHC II) (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- The T4-positive CTL clone HG-38 was used as the immunogen for the HLA-DQ antibody.
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亚型
- IgG2a, kappa
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anti-MHC Class II HLA-DQ (HLA-DQ) antibody
HLA-DQ 适用: 人, Pig FACS, IF, IHC 宿主: 兔 Monoclonal HLA-DQA1-2866R unconjugated Recombinant Antibody
anti-MHC Class II HLA-DQ (HLA-DQ) antibodyHLA-DQ 适用: 人, Pig FACS, IF 宿主: 小鼠 Monoclonal SPV-L3 unconjugated
anti-MHC Class II HLA-DQ (HLA-DQ) antibodyHLA-DQ 适用: 人, Pig FACS, IF, ELISA 宿主: 小鼠 Monoclonal SPM422 unconjugated
anti-MHC Class II HLA-DQ (HLA-DQ) antibodyHLA-DQ 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal B-K27 unconjugated
anti-MHC Class II HLA-DQ (HLA-DQ) antibodyHLA-DQ 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal B-K27 unconjugated
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应用备注
- Optimal dilution of the HLA-DQ antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the HLA-DQ antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- HLA DQ (HLA-DQ) (MHC Class II HLA-DQ (HLA-DQ))
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别名
- HLA-DQ
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背景
- Recognizes a DQ antigen, which is a dimer of 60 kDa. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons, exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.
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UniProt
- P01908
抗原
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