CXCR2 抗体
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北京 101111
Quick Overview for CXCR2 抗体 (ABIN302553)
抗原
See all CXCR2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects Interleukin 8 Receptor B (CXCR2) (IL8RB).
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Immunoaffinity Chromatography.
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免疫原
- IL8RB antibody was raised against Human CXCR2/IL8RB Genename: IL8RB
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应用备注
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Immunohistochemistry on Paraffin Sections: 5-10 μg/mL. This antibody was validated for use in immunohistochemistry on a panel of 21formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigenretrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides wereincubated with biotinylated secondary antibody, followed by alkalinephosphatase-streptavidin and chromogen.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.09 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
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- CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
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别名
- CD182 / IL8RB
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背景
- The IL8RB is a Chemokine Receptor also known as type 1 interleukin-8 receptor. There are three interleukin-8 receptors on chromosome 2: IL8RA (type 2), IL8RB (type 1), and a pseudogene. Results from mouse knock-out studies suggest that IL8RB may inhibit the expansion and development of neutrophils and B cells (Cacalano et al., 1994). IL8RB is a high-affinity receptor for IL8, and for GROalpha, beta, and gamma (Ahuja and Murphy, 1996).Synonyms: CDw128b, CXCR-2, CXCR2, GRO/MGSA receptor, IL-8 receptor type 2, IL8 receptor beta
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基因ID
- 3579
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NCBI登录号
- NP_001161770
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UniProt
- P25025
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途径
- cAMP Metabolic Process
抗原
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