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MALT1 抗体 (AA 701-808)

MALT1 适用: 人 WB, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal MT1-410 unconjugated
产品编号 ABIN3025292
发货至: 中国
  • 抗原 See all MALT1 抗体
    MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))
    抗原表位
    • 19
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    AA 701-808
    适用
    • 64
    • 18
    • 14
    • 1
    宿主
    • 43
    • 22
    • 1
    小鼠
    克隆类型
    • 43
    • 23
    单克隆
    标记
    • 38
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This MALT1 antibody is un-conjugated
    应用范围
    • 53
    • 23
    • 17
    • 13
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    • 12
    • 8
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    • 4
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    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Protein G purified monoclonal antibody
    免疫原
    A recombinant fragment (aa 701-808) was used as the immunogen for this antibody.
    克隆位点
    MT1-410
    亚型
    IgG1 kappa
    Top Product
    Discover our top product MALT1 Primary Antibody
  • 应用备注
    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.

    1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
    2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. FACS: 0.5-1 μg/million cells,IF: 1-2 μg/mL,WB: 0.5-1 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1),Prediluted format : incubate for 30 min at RT (2)

    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    1 mg/mL in 1X PBS, BSA free, sodium azide free
    储存液
    Azide free
    储存条件
    4 °C,-20 °C
    储存方法
    Store the MALT1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原
    MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))
    别名
    MALT1 (MALT1 产品)
    别名
    malt1 antibody, MALT1 antibody, mlt antibody, mlt1 antibody, MLT antibody, MLT1 antibody, A630046N12 antibody, D430033E09Rik antibody, MALT paracaspase 2 antibody, MALT1 paracaspase antibody, MALT1 paracaspase S homeolog antibody, paracaspase 3 antibody, malt2 antibody, MALT1 antibody, malt1.S antibody, Malt1 antibody, PCASP3 antibody
    背景
    Mucosa associated lymphoid tissue lymphoma translocation gene 1 is found in extranodal low-grade B cell lymphomas. It encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of the MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11,18)(q21,q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear < a href=../search_result.php?search_txt=bcl10>Bcl10, which mediates the oligomerization and activation of a caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.
    基因ID
    10892
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
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