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FTL 抗体 (AA 38-165)

This anti-FTL antibody is a 小鼠 单克隆 antibody detecting FTL in WB, IF, FACS 和 IHC (p). Suitable for 人.
产品编号 ABIN3025210
发货至: 中国

Quick Overview for FTL 抗体 (AA 38-165) (ABIN3025210)

抗原

See all FTL 抗体
FTL (Ferritin, Light Polypeptide (FTL))

适用

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宿主

  • 88
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小鼠

克隆类型

  • 105
  • 72
单克隆

标记

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This FTL antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

FTLC1-1
  • 抗原表位

    • 73
    • 16
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    AA 38-165

    纯化方法

    Protein G affinity chromatography

    免疫原

    Amino acids 38-165 of human FTL were used as the immunogen for this Ferritin antibody (light chain specific).

    亚型

    IgG2b
  • 应用备注

    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Ferritin antibody to be titered up or down for optimal performance.

    1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM Citrate Buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.\. Western blot: 1-2 μg/mL,FACS: 0.5-1 μg/10^6 cells,IF: 1-2 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 min at RT (1)

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Ferritin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    FTL (Ferritin, Light Polypeptide (FTL))

    别名

    Ferritin (Light Chain Specific)

    背景

    Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.

    基因ID

    2512

    途径

    Transition Metal Ion Homeostasis
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