CD6 抗体
Quick Overview for CD6 抗体 (ABIN3024446)
抗原
See all CD6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein G affinity chromatography
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免疫原
- A CD8+ cytotoxic T-cell clone was used as the immunogen for the CD6 antibody.
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亚型
- IgG1
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应用备注
- Optimal dilution of the CD6 antibody should be determined by the researcher.\. Western blot: 1-2 μg/mL, Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL
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限制
- 仅限研究用
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the CD6 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- CD6
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别名
- CD6
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背景
- CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular "scavenger receptor cysteine-rich" (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
抗原
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