CD11b 抗体
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北京 101111
Quick Overview for CD11b 抗体 (ABIN3024274)
抗原
See all CD11b (ITGAM) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- CD11b Antibody / MAC-1 / ITGAM (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- B10 mouse spleen cells enriched for T lymphocytes were used as the immunogen for this CD11b antibody.
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亚型
- IgG2b, kappa
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应用备注
- The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD11b antibody to be titered up or down for optimal performance.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the CD11b antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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别名
- CD11b
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背景
- CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin alpha-M (CD11b) combines with the Integrin beta-2 (CD18) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin alpha-M/beta-2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.
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途径
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
抗原
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