Recombinant CAD 抗体
Quick Overview for Recombinant CAD 抗体 (ABIN3024260)
抗原
See all CAD 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
纯化方法
- Protein A affinity chromatography
-
免疫原
- A recombinant full length human protein was used as the immunogen for the CAD antibody.
-
亚型
- IgG kappa
-
-
-
-
应用备注
-
Titering of the CAD antibody may be required for optimal performance.
1. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 min.\. Immunofluorescence: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
-
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/mL
-
缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
储存液
- Azide free
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store the CAD antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
-
-
- CAD (Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD))
-
别名
- CAD
-
背景
- Caldesmon is an actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration (By similarity). [UniProt]
-
途径
- Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process
抗原
-