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VLDLR 抗体 (C-Term)

This anti-VLDLR antibody is a 小鼠 单克隆 antibody detecting VLDLR in WB, FACS, IF 和 IHC (p). Suitable for 人 和 大鼠.
产品编号 ABIN3024045
发货至: 中国

Quick Overview for VLDLR 抗体 (C-Term) (ABIN3024045)

抗原

See all VLDLR 抗体
VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

适用

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人, 大鼠

宿主

  • 56
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小鼠

克隆类型

  • 54
  • 18
单克隆

标记

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This VLDLR antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

VLPR-1
  • 抗原表位

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    C-Term

    纯化方法

    Protein G affinity chromatography

    免疫原

    A human partial recombinant protein from the C-terminal region was used as the immunogen for this VLDLR antibody.

    亚型

    IgG1
  • 应用备注

    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the VLDLR antibody to be titered up or down for optimal performance.

    1. Staining of FFPE tissue is enhanced by boiling sections in 10  mM Tris with 1  mM EDTA,  pH 9 for 10-20 min followed by cooling at RT for 20 min.\. FACS: 0.5-1 μg/10^6 cells,IF: 1-2 μg/mL,Western blot: 1-2 μg/mL,IHC (FFPE): 1-2 μg/mL (1)

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the VLDLR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

    别名

    VLDLR

    背景

    Very Low Density Lipoprotein Receptor (VLDLR/VLDL receptor) is a member of the LDL receptor gene family which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDL receptor is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.

    基因ID

    7436

    途径

    Cellular Response to Molecule of Bacterial Origin
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