UACA 抗体
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北京 101111
Quick Overview for UACA 抗体 (ABIN3024023)
抗原
See all UACA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein G affinity chromatography
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免疫原
- Nuclei of myeloid leukemia biopsy cells were used as the immunogen for the UACA antibody.
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亚型
- IgG1 kappa
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应用备注
- Optimal dilution of the UACA antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Western blot: 0.5-1 μg/mL
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the UACA antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- UACA (Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA))
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别名
- UACA
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背景
- UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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