dsDNA 抗体
The 小鼠 单克隆 anti-dsDNA antibody is suitable to detect dsDNA in samples from 人. It has been validated for IHC (p).
1 image
产品编号 ABIN3023886
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for dsDNA 抗体 (ABIN3023886)
抗原
dsDNA
(Double-Stranded DNA (dsDNA))
适用
人
宿主
小鼠
克隆类型
单克隆
标记
This dsDNA antibody is un-conjugated
应用范围
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
质量等级
Carrier-free
克隆位点
DSD-958
-
-
原理
- Double Stranded DNA Antibody (azide and preservative free)
-
产品特性
- This mAb recognizes the double stranded DNA in human cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells. This mAb produces a homogeneous staining pattern in the nucleus of normal and malignant cells. Deoxyribonucleic acid (DNA) is a nucleic acid that stores long-term information regarding the development and function of all known living organisms. DNA consists of two long nucleotide polymers, which are composed of four bases, namely adenine, thymine, guanine and cytosine, all of which are flanked by a phosphate-deoxyribose backbone. Normally, DNA exists as a double-stranded (ds) molecule that forms in the shape of a double helix, allowing the bases and the backbone of the two strands to interact, thus forming a polynucleotide. When the double helix is unwound (either by enzymes or heat), DNA exists as a single-stranded (ss) molecule that is less stable than the double helix, but is necessary for protein access to DNA bases. Double stranded DNA markers are useful tools in biology research and aid in the study of DNA behavior and characteristics.
-
纯化方法
- Protein G affinity chromatography
-
免疫原
- Nuclei of Burkitt's cells were used as the immunogen for the Double Stranded DNA antibody.
-
亚型
- IgG3, kappa
-
-
anti-Double-Stranded DNA (dsDNA) antibody
dsDNA 适用: 人 FACS, IHC 宿主: 小鼠 Monoclonal 121-3 unconjugated
-
-
应用备注
-
Optimal dilution of the Double Stranded DNA antibody should be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 min.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
储存液
- Azide free
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store the Double Stranded DNA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
-
-
- dsDNA (Double-Stranded DNA (dsDNA))
-
别名
- Double Stranded DNA
-
物质类
- Nucleotide
-
背景
- This mAb recognizes the double stranded DNA in human cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells. This mAb produces a homogeneous staining pattern in the nucleus of normal and malignant cells. Deoxyribonucleic acid (DNA) is a nucleic acid that stores long-term information regarding the development and function of all known living organisms. DNA consists of two long nucleotide polymers, which are composed of four bases, namely adenine, thymine, guanine and cytosine, all of which are flanked by a phosphate-deoxyribose backbone. Normally, DNA exists as a double-stranded (ds) molecule that forms in the shape of a double helix, allowing the bases and the backbone of the two strands to interact, thus forming a polynucleotide. When the double helix is unwound (either by enzymes or heat), DNA exists as a single-stranded (ss) molecule that is less stable than the double helix, but is necessary for protein access to DNA bases. Double stranded DNA markers are useful tools in biology research and aid in the study of DNA behavior and characteristics.
抗原
-
You are here:
