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DNMT1 抗体 (pSer714)

This anti-DNMT1 antibody is a 兔 多克隆 antibody detecting DNMT1 in WB 和 IF. Suitable for 人.
产品编号 ABIN3023526
发货至: 中国

Quick Overview for DNMT1 抗体 (pSer714) (ABIN3023526)

抗原

See all DNMT1 抗体
DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

适用

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宿主

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克隆类型

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多克隆

标记

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This DNMT1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    pSer714

    序列

    MPSPK

    交叉反应

    产品特性

    Phosphorylated Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic phosphorylated peptide around S714 of human Phospho-DNMT1-pS714 (NP_001370.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

    别名

    DNMT1

    背景

    This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.,ADCADN,AIM,CXXC9,DNMT,HSN1E,MCMT,m.HsaI,DNMT1,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,DNA methylation,Protein phosphorylation,DNMT1

    分子量

    144 kDa/183 kDa/184 kDa

    基因ID

    1786

    UniProt

    P26358

    途径

    SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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