Histone 3 抗体 (H3K4me3)
Quick Overview for Histone 3 抗体 (H3K4me3) (ABIN3023254)
抗原
See all Histone 3 (H3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- H3K4me3
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Methylated Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic methylated peptide corresponding to residues surrounding K4 of human histone H3
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亚型
- IgG
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应用备注
- DB,1:500 - 1:2000,WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200,ChIP,1:20 - 1:100,ChIP-seq,1:20 - 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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Automated in situ chromatin profiling efficiently resolves cell types and gene regulatory programs." in: Epigenetics & chromatin, Vol. 11, Issue 1, pp. 74, (2019) (PubMed).
: "Histone demethylase LSD1 regulates bone mass by controlling WNT7B and BMP2 signaling in osteoblasts." in: Bone research, Vol. 6, pp. 14, (2018) (PubMed).
: "Setd7 and its contribution to Boron-induced bone regeneration in Boron-mesoporous bioactive glass scaffolds." in: Acta biomaterialia, Vol. 73, pp. 522-530, (2018) (PubMed).
: "iTRAQ-Based Proteomic Analysis of Neonatal Kidney from Offspring of Protein Restricted Rats Reveals Abnormalities in Intraflagellar Transport Proteins." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 44, Issue 1, pp. 185-199, (2018) (PubMed).
: "Ascorbic acid induces global epigenetic reprogramming to promote meiotic maturation and developmental competence of porcine oocytes." in: Scientific reports, Vol. 8, Issue 1, pp. 6132, (2018) (PubMed).
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Automated in situ chromatin profiling efficiently resolves cell types and gene regulatory programs." in: Epigenetics & chromatin, Vol. 11, Issue 1, pp. 74, (2019) (PubMed).
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- Histone 3 (H3)
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别名
- Histone H3
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背景
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.,H3.4,H3/g,H3FT,H3t,HIST3H3,Histone H3,HIST1H3A,Signal Transduction,MAPK-Erk Signaling Pathway,MAPK-P38 Signaling Pathway,Epigenetics & Nuclear Signaling,Epigenetic Modifications,Methylation,Histone H3
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分子量
- 15 kDa
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基因ID
- 8290
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UniProt
- Q16695
抗原
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