IRF3 抗体
Quick Overview for IRF3 抗体 (ABIN3023115)
抗原
See all IRF3 抗体适用
宿主
克隆类型
标记
应用范围
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                                            交叉反应
- 人, 小鼠, 大鼠
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                                            产品特性
- Polyclonal Antibodies
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                                            免疫原
- A synthetic peptide of human IRF3
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                                            亚型
- IgG
 
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                                            应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            注意事项
- Avoid freeze / thaw cycles
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                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
 
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                                            : "Seneca Valley Virus Suppresses Host Type I Interferon Production by Targeting Adaptor Proteins MAVS, TRIF, and TANK for Cleavage."    in: Journal of virology, Vol. 91, Issue 16, (2017)         (PubMed).        
 : "Ubiquitin-specific proteases 25 negatively regulates virus-induced type I interferon signaling." in: PLoS ONE, Vol. 8, Issue 11, pp. e80976, (2013) (PubMed).
 
 
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                                            : "Seneca Valley Virus Suppresses Host Type I Interferon Production by Targeting Adaptor Proteins MAVS, TRIF, and TANK for Cleavage."    in: Journal of virology, Vol. 91, Issue 16, (2017)         (PubMed).        
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    - IRF3 (Interferon Regulatory Factor 3 (IRF3))
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                                            别名
- IRF3
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                                            背景
- This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,IIAE7,IRF3,Epigenetics & Nuclear Signaling,Transcription Factors,Immunology & Inflammation,Cytokines,Interferons,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,IRF3
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                                            分子量
- 12 kDa/16 kDa/33 kDa/47 kDa/49 kDa
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                                            基因ID
- 3661
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                                            UniProt
- Q14653
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                                            途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
 抗原
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