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TYK2 抗体 (AA 750-850)

This anti-TYK2 antibody is a 兔 多克隆 antibody detecting TYK2 in WB, IHC 和 IF. Suitable for 人.
产品编号 ABIN3022988
发货至: 中国

Quick Overview for TYK2 抗体 (AA 750-850) (ABIN3022988)

抗原

See all TYK2 抗体
TYK2 (Tyrosine Kinase 2 (TYK2))

适用

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宿主

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克隆类型

  • 76
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多克隆

标记

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This TYK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 750-850

    序列

    GTSPFIKLSD PGVGLGALSR EERVERIPWL APECLPGGAN SLSTAMDKWG FGATLLEICF DGEAPLQSRS PSEKEHFYQR QHRLPEPSCP QLATLTSQCL T

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 750-850 of human TYK2 (NP_003322.3).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    TYK2 (Tyrosine Kinase 2 (TYK2))

    别名

    TYK2

    背景

    This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.,TYK2,IMD35,JTK1,Signal Transduction,Kinase,Tyrosine kinases,ErbB-HER Signaling Pathway,Immunology & Inflammation,TYK2

    分子量

    133 kDa

    基因ID

    7297

    UniProt

    P29597

    途径

    JAK/STAT Signaling, Hepatitis C
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