DDB2 抗体 (AA 1-315)
(1 reference)Quick Overview for DDB2 抗体 (AA 1-315) (ABIN3022632)
抗原
See all DDB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-315
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序列
- MAPKKRPETQ KTSEIVLRPR NKRSRSPLEL EPEAKKLCAK GSGPSRRCDS DCLWVGLAGP QILPPCRSIV RTLHQHKLGR ASWPSVQQGL QQSFLHTLDS YRILQKAAPF DRRATSLAWH PTHPSTVAVG SKGGDIMLWN FGIKDKPTFI KGIGAGGSIT GLKFNPLNTN QFYASSMEGT TRLQDFKGNI LRVFASSDTI NIWFCSLDVS ASSRMVVTGD NVGNVILLNM DGKELWNLRM HKKKVTHVAL NPCCDWFLAT ASVDQTVKIW DLRQVRGKAS FLYSLPHRHP VNAACFSPDG ARLLTTDQKS EIRVY
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-315 of human DDB2 (NP_000098.1).
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亚型
- IgG
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anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) (AA 201-300) antibody
DDB2 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) antibodyDDB2 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) (AA 166-383) antibodyDDB2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) (AA 1-427) antibodyDDB2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) antibodyDDB2 适用: 人 WB, ICC, DB 宿主: 小鼠 Monoclonal 2246C4a unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) antibodyDDB2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) (AA 1-185) antibodyDDB2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) (AA 1-109) antibodyDDB2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F11 unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) (C-Term) antibodyDDB2 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) (C-Term) antibodyDDB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "RNA m6A methylation regulates the ultraviolet-induced DNA damage response." in: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).
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: "RNA m6A methylation regulates the ultraviolet-induced DNA damage response." in: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).
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- DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))
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别名
- DDB2
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背景
- This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.,DDB2,DDBB,UV-DDB2,XPE,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cell Biology & Developmental Biology,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,DDB2
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分子量
- 17 kDa/26 kDa/40 kDa/47 kDa
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基因ID
- 1643
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UniProt
- Q92466
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途径
- DNA Damage Repair
抗原
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