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KEAP1 抗体 (AA 325-624)

This anti-KEAP1 antibody is a 兔 多克隆 antibody detecting KEAP1 in WB, IHC 和 IF. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN3022609
发货至: 中国

Quick Overview for KEAP1 抗体 (AA 325-624) (ABIN3022609)

抗原

See all KEAP1 抗体
KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

适用

  • 92
  • 65
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宿主

  • 92
  • 10
  • 1

克隆类型

  • 90
  • 13
多克隆

标记

  • 55
  • 8
  • 5
  • 5
  • 2
  • 2
  • 2
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  • 2
  • 2
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  • 1
  • 1
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This KEAP1 antibody is un-conjugated

应用范围

  • 86
  • 43
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  • 26
  • 16
  • 13
  • 11
  • 9
  • 6
  • 6
  • 2
  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 15
    • 13
    • 12
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 325-624

    序列

    GRLIYTAGGY FRQSLSYLEA YNPSDGTWLR LADLQVPRSG LAGCVVGGLL YAVGGRNNSP DGNTDSSALD CYNPMTNQWS PCAPMSVPRN RIGVGVIDGH IYAVGGSHGC IHHNSVERYE PERDEWHLVA PMLTRRIGVG VAVLNRLLYA VGGFDGTNRL NSAECYYPER NEWRMITAMN TIRSGAGVCV LHNCIYAAGG YDGQDQLNSV ERYDVETETW TFVAPMKHRR SALGITVHQG RIYVLGGYDG HTFLDSVECY DPDTDTWSEV TRMTSGRSGV GVAVTMEPCR KQIDQQNCTC

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 325-624 of human KEAP1 (NP_036421.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Chen, Li, Fan, Cao, Yao, Xu: "Selenium antagonizes cadmium-induced apoptosis in chicken spleen but not involving Nrf2-regulated antioxidant response." in: Ecotoxicology and environmental safety, Vol. 145, pp. 503-510, (2017) (PubMed).

    Xu, Zhang, Lu, Deng, Zhao, Zhao, Zhao: "Prevention of Hippocampal Neuronal Damage and Cognitive Function Deficits in Vascular Dementia by Dextromethorphan." in: Molecular neurobiology, Vol. 53, Issue 5, pp. 3494-502, (2016) (PubMed).

  • 抗原

    KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

    别名

    KEAP1

    背景

    This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.,KEAP1,INrf2,KLHL19,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,KEAP1

    分子量

    69 kDa

    基因ID

    9817

    UniProt

    Q14145

    途径

    Maintenance of Protein Location
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