Dynactin 1 抗体 (AA 945-1139)
Quick Overview for Dynactin 1 抗体 (AA 945-1139) (ABIN3022542)
抗原
See all Dynactin 1 (DCTN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 945-1139
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序列
- PGLVKDSPLL LQQISAMRLH ISQLQHENSI LKGAQMKASL ASLPPLHVAK LSHEGPGSEL PAGALYRKTS QLLETLNQLS THTHVVDITR TSPAAKSPSA QLMEQVAQLK SLSDTVEKLK DEVLKETVSQ RPGATVPTDF ATFPSSAFLR AKEEQQDDTV YMGKVTFSCA AGFGQRHRLV LTQEQLHQLH SRLIS
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 945-1139 of human DCTN1 (NP_001128513.1).
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亚型
- IgG
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anti-Dynactin 1 (DCTN1) (C-Term) antibody
Verified DCTN1 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Dynactin 1 (DCTN1) (C-Term) antibodyDCTN1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dynactin 1 (DCTN1) (AA 1084-1278) antibodyDCTN1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dynactin 1 (DCTN1) (C-Term) antibodyDCTN1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dynactin 1 (DCTN1) (N-Term) antibodyDCTN1 适用: 人 WB, IP 宿主: 小鼠 Monoclonal unconjugated
anti-Dynactin 1 (DCTN1) (AA 1216-1278) antibodyDCTN1 适用: 人 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dynactin 1 (DCTN1) antibodyDCTN1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Dynactin 1 (DCTN1) (AA 1-198) antibodyDCTN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E4-1C2 unconjugated
anti-Dynactin 1 (DCTN1) (C-Term) antibodyDCTN1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IP,1:50 - 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Dynactin 1 (DCTN1)
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别名
- DCTN1
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背景
- This gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA).,DCTN1,DAP-150,DP-150,P135,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cytoskeleton,Motor Proteins,Neuroscience,Neurodegenerative Diseases,DCTN1
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分子量
- 126 kDa/127 kDa/136 kDa/138 kDa/140 kDa/141 kDa
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基因ID
- 1639
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UniProt
- Q14203
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途径
- M Phase, ER-Nucleus Signaling
抗原
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