ICAM1 抗体
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北京 101111
Quick Overview for ICAM1 抗体 (ABIN302240)
抗原
See all ICAM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Synonyms: ICAM-1, Intercellular adhesion molecule 1, Major Group Rhinovirus Receptor
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纯化方法
- Protein A Affinity Chromatography
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免疫原
- Raji cells and spleen cells fused with NS1 cells
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亚型
- IgG2b
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应用备注
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Flow Cytometry. Western blot. Immunohistochemistry (paraffin sections): 10-20 μg/mL (Prolonged fixation in bufferedformalin can destroy the epitope, hight temperature antigen unmasking technique isrequired). Immunohistochemistry (frozen sections): 5-20 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Azide free PBS preserved by filter sterilization, pH ~7.4
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储存液
- Azide free
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
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别名
- CD54 / ICAM1
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背景
- CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.Synonyms: ICAM-1, Intercellular adhesion molecule 1, Major Group Rhinovirus Receptor
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UniProt
- P05362
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途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
抗原
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