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RENT1/UPF1 抗体 (AA 270-370)

This anti-RENT1/UPF1 antibody (ABIN3022069) is a Rabbit Polyclonal antibody detecting RENT1/UPF1 in WB, IF, IP. Suitable for Human.
产品编号 ABIN3022069
发货至: 中国

Quick Overview for RENT1/UPF1 抗体 (AA 270-370) (ABIN3022069)

抗原

See all RENT1/UPF1 (UPF1) 抗体
RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

适用

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宿主

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克隆类型

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多克隆

标记

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This RENT1/UPF1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
  • 抗原表位

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    AA 270-370

    序列

    KENPSATLED LEKPGVDEEP QHVLLRYEDA YQYQNIFGPL VKLEADYDKK LKESQTQDNI TVRWDLGLNK KRIAYFTLPK TDSDMRLMQG DEICLRYKGD L

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 270-370 of human UPF1/RENT1 (NP_002902.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

    别名

    UPF1

    背景

    This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants.,UPF1,HUPF1,NORF1,RENT1,pNORF1,smg-2,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Apoptosis,UPF1

    分子量

    123 kDa/124 kDa

    基因ID

    5976

    UniProt

    Q92900

    途径

    SARS-CoV-2 Protein Interactome
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