HMOX1 抗体 (AA 1-288)
Quick Overview for HMOX1 抗体 (AA 1-288) (ABIN3021907)
抗原
See all HMOX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-288
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序列
- MERPQPDSMP QDLSEALKEA TKEVHTQAEN AEFMRNFQKG QVTRDGFKLV MASLYHIYVA LEEEIERNKE SPVFAPVYFP EELHRKAALE QDLAFWYGPR WQEVIPYTPA MQRYVKRLHE VGRTEPELLV AHAYTRYLGD LSGGQVLKKI AQKALDLPSS GEGLAFFTFP NIASATKFKQ LYRSRMNSLE MTPAVRQRVI EEAKTAFLLN IQLFEELQEL LTHDTKDQSP SRAPGLRQRA SNKVQDSAPV ETPRGKPPLN TRSQAPLLRW VLTLSFLVAT VAVGLYAM
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-288 of human Heme Oxygenase 1 (HO-1/HMOX1) (NP_002124.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Astaxanthin Promotes Nrf2/ARE Signaling to Inhibit HG-Induced Renal Fibrosis in GMCs." in: Marine drugs, Vol. 16, Issue 4, (2018) (PubMed).
: "Physiological functions of ferroportin in the regulation of renal iron recycling and ischemic acute kidney injury." in: American journal of physiology. Renal physiology, Vol. 315, Issue 4, pp. F1042-F1057, (2018) (PubMed).
: "Boron Affects the Development of the Kidney Through Modulation of Apoptosis, Antioxidant Capacity, and Nrf2 Pathway in the African Ostrich Chicks." in: Biological trace element research, Vol. 186, Issue 1, pp. 226-237, (2018) (PubMed).
: "GYY4137 protects against myocardial ischemia/reperfusion injury via activation of the PHLPP-1/Akt/Nrf2 signaling pathway in diabetic mice." in: The Journal of surgical research, Vol. 225, pp. 29-39, (2018) (PubMed).
: "Paeonol Ameliorates Diabetic Renal Fibrosis Through Promoting the Activation of the Nrf2/ARE Pathway via Up-Regulating Sirt1." in: Frontiers in pharmacology, Vol. 9, pp. 512, (2018) (PubMed).
: "Connexin43 regulates high glucose-induced expression of fibronectin, ICAM-1 and TGF-β1 via Nrf2/ARE pathway in glomerular mesangial cells." in: Free radical biology & medicine, Vol. 102, pp. 77-86, (2016) (PubMed).
: "Trimetazidine prevents macrophage-mediated septic myocardial dysfunction via activation of the histone deacetylase sirtuin 1." in: British journal of pharmacology, Vol. 173, Issue 3, pp. 545-61, (2016) (PubMed).
: "Diabetes blocks the cardioprotective effects of sevoflurane postconditioning by impairing Nrf2/Brg1/HO-1 signaling." in: European journal of pharmacology, Vol. 779, pp. 111-21, (2016) (PubMed).
: "Mst1 regulates hepatic lipid metabolism by inhibiting Sirt1 ubiquitination in mice." in: Biochemical and biophysical research communications, Vol. 471, Issue 4, pp. 444-9, (2016) (PubMed).
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: "Astaxanthin Promotes Nrf2/ARE Signaling to Inhibit HG-Induced Renal Fibrosis in GMCs." in: Marine drugs, Vol. 16, Issue 4, (2018) (PubMed).
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- HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))
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别名
- HMOX1
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背景
- Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.,HMOX1,HMOX1D,HO-1,HSP32,bK286B10,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Immunology & Inflammation,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Cardiovascular,Blood,Hypoxia,HMOX1
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分子量
- 32 kDa
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基因ID
- 3162
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UniProt
- P09601
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途径
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome
抗原
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