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SOD2 抗体 (AA 25-222)

This anti-SOD2 antibody is a 兔 多克隆 antibody detecting SOD2 in WB, IHC 和 IF. Suitable for 人. This Primary Antibody has been cited in 8+ publications.
产品编号 ABIN3021904
发货至: 中国

Quick Overview for SOD2 抗体 (AA 25-222) (ABIN3021904)

抗原

See all SOD2 抗体
SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))

适用

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宿主

  • 148
  • 24
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  • 1

克隆类型

  • 141
  • 36
多克隆

标记

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This SOD2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 25-222

    序列

    KHSLPDLPYD YGALEPHINA QIMQLHHSKH HAAYVNNLNV TEEKYQEALA KGDVTAQIAL QPALKFNGGG HINHSIFWTN LSPNGGGEPK GELLEAIKRD FGSFDKFKEK LTAASVGVQG SGWGWLGFNK ERGHLQIAAC PNQDPLQGTT GLIPLLGIDV WEHAYYLQYK NVRPDYLKAI WNVINWENVT ERYMACKK

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 25-222 of human SOD2 (NP_000627.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Zhang, Geng, Liu, Li, Gao, Liu, Fang, Chang: "Celastrol ameliorates liver metabolic damage caused by a high-fat diet through Sirt1." in: Molecular metabolism, Vol. 6, Issue 1, pp. 138-147, (2018) (PubMed).

    Hu, Nie, Chen, Xie, Fan, Wang, Long, Yan, Zhong, Yan: "Leucine reduces reactive oxygen species levels via an energy metabolism switch by activation of the mTOR-HIF-1α pathway in porcine intestinal epithelial cells." in: The international journal of biochemistry & cell biology, Vol. 89, pp. 42-56, (2017) (PubMed).

    Zhong, Wang, Liu, Li, Huang, Zhou, Lin, Lin, Yang: "Ganoderma lucidum polysaccharide peptide prevents renal ischemia reperfusion injury via counteracting oxidative stress." in: Scientific reports, Vol. 5, pp. 16910, (2016) (PubMed).

    Chen, An, Chen, Ye, Shen, Han, Zhang, Gao: "Chronic Exercise Training Improved Aortic Endothelial and Mitochondrial Function via an AMPKα2-Dependent Manner." in: Frontiers in physiology, Vol. 7, pp. 631, (2016) (PubMed).

    Geng, Zhang, Gao, Tao, Zhang, Liu, Fang, Chang: "Mst1 regulates hepatic lipid metabolism by inhibiting Sirt1 ubiquitination in mice." in: Biochemical and biophysical research communications, Vol. 471, Issue 4, pp. 444-9, (2016) (PubMed).

    Zhang, Ouyang, Wang, Shi, Ouyang, Chen, Xiao, Fang: "Mycobacterium tuberculosis Rv2185c contributes to nuclear factor-κB activation." in: Molecular immunology, Vol. 66, Issue 2, pp. 147-53, (2015) (PubMed).

    Zhu, Dong, Sun, Ma, Yang, Zhu, Xu: "Rejuvenation of MPTP-induced human neural precursor cell senescence by activating autophagy." in: Biochemical and biophysical research communications, Vol. 464, Issue 2, pp. 526-33, (2015) (PubMed).

    Liu, Cui, Li, Xu, Zuo, Fang, Chang: "Cobalt protoporphyrin induces HO-1 expression mediated partially by FOXO1 and reduces mitochondria-derived reactive oxygen species production." in: PLoS ONE, Vol. 8, Issue 11, pp. e80521, (2014) (PubMed).

  • 抗原

    SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))

    别名

    SOD2

    背景

    This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.,IPO-B,IPOB,MNSOD,MVCD6,Mn-SOD,SOD2,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Hypoxia,SOD2

    分子量

    18 kDa/19 kDa/20 kDa/24 kDa

    基因ID

    6648

    UniProt

    P04179

    途径

    Sensory Perception of Sound, Transition Metal Ion Homeostasis, Negative Regulation of intrinsic apoptotic Signaling
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