ACTN1 抗体 (AA 1-330)
(3 references)Quick Overview for ACTN1 抗体 (AA 1-330) (ABIN3021587)
抗原
See all ACTN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-330
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序列
- MDHYDSQQTN DYMQPEEDWD RDLLLDPAWE KQQRKTFTAW CNSHLRKAGT QIENIEEDFR DGLKLMLLLE VISGERLAKP ERGKMRVHKI SNVNKALDFI ASKGVKLVSI GAEEIVDGNV KMTLGMIWTI ILRFAIQDIS VEETSAKEGL LLWCQRKTAP YKNVNIQNFH ISWKDGLGFC ALIHRHRPEL IDYGKLRKDD PLTNLNTAFD VAEKYLDIPK MLDAEDIVGT ARPDEKAIMT YVSSFYHAFS GAQKAETAAN RICKVLAVNQ ENEQLMEDYE KLASDLLEWI RRTIPWLENR VPENTMHAMQ QKLEDFRDYR RLHKPPKVQE
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交叉反应
- 人, 猴, 小鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-330 of human ACTN1 (NP_001123477.1).
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亚型
- IgG
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anti-Actinin, alpha 1 (ACTN1) antibody
ACTN1 适用: 人, 小鼠, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) antibodyACTN1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) (AA 543-639) antibodyACTN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F1 unconjugated
anti-Actinin, alpha 1 (ACTN1) antibodyACTN1 适用: 人 WB, IHC (p), IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) antibodyACTN1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) (AA 28-260) antibodyACTN1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) (AA 1-204) antibodyACTN1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) (AA 1-892) antibodyACTN1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) (AA 543-639) antibodyACTN1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) (AA 596-609) antibodyVerified ACTN1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Protein kinase A inhibitor, H89, significantly enhances survival rate of dissociated human embryonic stem cells following cryopreservation." in: Cell proliferation, Vol. 49, Issue 5, pp. 589-98, (2017) (PubMed).
: "Protein kinase A inhibitor, H89, enhances survival and clonogenicity of dissociated human embryonic stem cells through Rho-associated coiled-coil containing protein kinase (ROCK) inhibition." in: Human reproduction (Oxford, England), Vol. 31, Issue 4, pp. 832-43, (2016) (PubMed).
: "Sensitivity of human embryonic stem cells to different conditions during cryopreservation." in: Cryobiology, Vol. 71, Issue 3, pp. 486-92, (2016) (PubMed).
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: "Protein kinase A inhibitor, H89, significantly enhances survival rate of dissociated human embryonic stem cells following cryopreservation." in: Cell proliferation, Vol. 49, Issue 5, pp. 589-98, (2017) (PubMed).
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- ACTN1 (Actinin, alpha 1 (ACTN1))
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别名
- ACTN1
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背景
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.,ACTN1,BDPLT15,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Microfilaments,Immunology & Inflammation,T Cell Receptor Signaling Pathway,Stem Cells,ACTN1
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分子量
- 102 kDa/103 kDa/105 kDa/107 kDa
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基因ID
- 87
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UniProt
- P12814
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途径
- Cell-Cell Junction Organization
抗原
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