TLR7 抗体 (AA 30-230)
Quick Overview for TLR7 抗体 (AA 30-230) (ABIN3021247)
抗原
See all TLR7 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 30-230
-
序列
- FPKTLPCDVT LDVPKNHVIV DCTDKHLTEI PGGIPTNTTN LTLTINHIPD ISPASFHRLD HLVEIDFRCN CVPIPLGSKN NMCIKRLQIK PRSFSGLTYL KSLYLDGNQL LEIPQGLPPS LQLLSLEANN IFSIRKENLT ELANIEILYL GQNCYYRNPC YVSYSIEKDA FLNLTKLKVL SLKDNNVTAV PTVLPSTLTE L
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Polyclonal Antibodies
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 30-230 of human TLR7 (NP_057646.1).
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid freeze / thaw cycles
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
-
: "TLR7 Mediates HIV-1 Tat-Induced Cellular Senescence in Human Astrocytes." in: Aging cell, Vol. 24, Issue 7, pp. e70086, (2025) (PubMed).
-
: "TLR7 Mediates HIV-1 Tat-Induced Cellular Senescence in Human Astrocytes." in: Aging cell, Vol. 24, Issue 7, pp. e70086, (2025) (PubMed).
-
- TLR7 (Toll-Like Receptor 7 (TLR7))
-
别名
- TLR7
-
背景
- The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.,TLR7,TLR7-like,Epigenetics & Nuclear Signaling,Signal Transduction,Immunology & Inflammation,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,TLR7
-
分子量
- 120 kDa
-
基因ID
- 51284
-
UniProt
- Q9NYK1
-
途径
- TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
-