RAP1A 抗体 (AA 50-150)
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北京 101111
Quick Overview for RAP1A 抗体 (AA 50-150) (ABIN3021200)
抗原
See all RAP1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-150
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序列
- QCMLEILDTA GTEQFTAMRD LYMKNGQGFA LVYSITAQST FNDLQDLREQ ILRVKDTEDV PMILVGNKCD LEDERVVGKE QGQNLARQWC NCAFLESSAK S
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Rap1A (NP_002875.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))
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别名
- RAP1A
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背景
- This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants.,RAP1A,C21KG,G-22K,KREV-1,KREV1,RAP1,SMGP21,Signal Transduction,G protein signaling,Signal Transduction,G2/M DNA Damage Checkpoint,MAPK-Erk Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,RAP1A
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分子量
- 20 kDa
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基因ID
- 5906
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UniProt
- P62834
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途径
- TCR Signaling, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor
抗原
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